› 2mq2

Solution NMR

Cysteine Deleted Protegrin-1 (CDP-1): Anti-bacterial Activity, Outer-Membrane Disruption and Selectivity

Released:
DOI: 10.2210/pdb2mq2/pdb
PDB entry 2mq2 coloured by chain, ensemble of 20 models, front view.
PDB entry 2mq2 coloured by chain, ensemble of 20 models, side view.
PDB entry 2mq2 coloured by chain, ensemble of 20 models, top view.
Source organism: Synthetic construct
Primary publication:
Cysteine deleted protegrin-1 (CDP-1): anti-bacterial activity, outer-membrane disruption and selectivity.
Mohanram H, Bhattacharjya S
Biochim Biophys Acta 1840 3006-16 (2014)
PMID: 24997421

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-163014 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CDP-1 peptide, Cysteine Deleted Protegrin-1 Chain: A
Molecule details ›
Chain: A
Length: 14 amino acids
Theoretical weight: 1.75 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 29%
Refinement method: simulated annealing
Expression system: Not provided

Quick links

Citations

7 review citations

Antimicrobial peptides: Promising alternatives in the post feeding antibiotic era.
Wang et al. (2019)
6 more

1 mention without citation

The role of the jaw subdomain of peptidoglycan glycosyltransferases for lipid II polymerization.
Punekar et al. (2018)