› 2mtk

Solution NMR

NMR structure of the III-IV-V three-way junction from the VS ribozyme and identification of magnesium-binding sites using paramagnetic relaxation enhancement

Released:
DOI: 10.2210/pdb2mtk/pdb
PDB entry 2mtk coloured by chain, ensemble of 21 models, front view.
PDB entry 2mtk coloured by chain, ensemble of 21 models, side view.
PDB entry 2mtk coloured by chain, ensemble of 21 models, top view.
Source organism: Neurospora crassa
Primary publication:
Nuclear magnetic resonance structure of the III-IV-V three-way junction from the Varkud satellite ribozyme and identification of magnesium-binding sites using paramagnetic relaxation enhancement.
Bonneau E, Legault P
Biochemistry 53 6264-75 (2014)
PMID: 25238589

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-196507 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
RNA (47-MER) Chain: A
Molecule details ›
Chain: A
Length: 47 nucleotides
Theoretical weight: 15.12 KDa
Source organism: Neurospora crassa
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand MG 6 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 76%
Refinement method: simulated annealing
Expression system: Not provided

Quick links

Citations

2 review citations

Principles for targeting RNA with drug-like small molecules.
Warner et al. (2018)
1 more

3 mentions without citation

Insights into RNA structure and dynamics from recent NMR and X-ray studies of the Neurospora Varkud satellite ribozyme.
Dagenais et al. (2017)
2 more