› 2mv6

Solution NMR

Solution structure of the transmembrane domain and the juxta-membrane domain of the Erythropoietin Receptor in micelles

Released:
DOI: 10.2210/pdb2mv6/pdb
PDB entry 2mv6 coloured by chain, ensemble of 20 models, front view.
PDB entry 2mv6 coloured by chain, ensemble of 20 models, side view.
PDB entry 2mv6 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Structural insight into the transmembrane domain and the juxtamembrane region of the erythropoietin receptor in micelles.
Li Q, Wong YL, Huang Q, Kang C
Biophys J 107 2325-36 (2014)
PMID: 25418301

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148525 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Erythropoietin receptor Chain: A
Molecule details ›
Chain: A
Length: 49 amino acids
Theoretical weight: 5.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P19235 (Residues: 237-284; Coverage: 10%)
Gene name: EPOR

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 43%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

4 review citations

Progress and prospects for structural studies of transmembrane interactions in single-spanning receptors.
Trenker et al. (2016)
3 more

4 mentions without citation

Structural insight into the transmembrane domain and the juxtamembrane region of the erythropoietin receptor in micelles.
Li et al. (2014)
3 more