› 2mxb

Solution NMR

Structure of the transmembrane domain of the mouse erythropoietin receptor

Released:
DOI: 10.2210/pdb2mxb/pdb
PDB entry 2mxb coloured by chain, ensemble of 20 models, front view.
PDB entry 2mxb coloured by chain, ensemble of 20 models, side view.
PDB entry 2mxb coloured by chain, ensemble of 20 models, top view.
Source organism: Mus musculus
Primary publication:
Solution structure of the transmembrane domain of the mouse erythropoietin receptor in detergent micelles.
Li Q, Wong YL, Yueqi Lee M, Li Y, Kang C
Sci Rep 5 13586 (2015)
PMID: 26316120

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147068 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Erythropoietin receptor Chain: A
Molecule details ›
Chain: A
Length: 55 amino acids
Theoretical weight: 6.25 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P14753 (Residues: 236-283; Coverage: 10%)
Gene name: Epor

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 62%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

3 review citations

Rethinking JAK2 inhibition: towards novel strategies of more specific and versatile Janus kinase inhibition.
Leroy et al. (2017)
2 more

1 mention without citation

Solution structure of the transmembrane domain of the mouse erythropoietin receptor in detergent micelles.
Li et al. (2015)