› 2mxf

Solution NMR

Structure of the DNA complex of the C-Terminal domain of MvaT

Released:
DOI: 10.2210/pdb2mxf/pdb
PDB entry 2mxf coloured by chain, ensemble of 20 models, front view.
PDB entry 2mxf coloured by chain, ensemble of 20 models, side view.
PDB entry 2mxf coloured by chain, ensemble of 20 models, top view.
Source organism: Pseudomonas aeruginosa PAO1
Primary publication:
A Novel AT-Rich DNA Recognition Mechanism for Bacterial Xenogeneic Silencer MvaT.
Ding P, McFarland KA, Jin S, Tong G, Duan B, Yang A, Hughes TR, Liu J, Dove SL, Navarre WW, Xia B
PLoS Pathog 11 e1004967 (2015)
PMID: 26068099

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-115644 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct DNA molecule
Macromolecules (2 distinct):
MvaT Chain: A
Molecule details ›
Chain: A
Length: 55 amino acids
Theoretical weight: 6.46 KDa
Source organism: Pseudomonas aeruginosa PAO1
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9HW86 (Residues: 77-124; Coverage: 39%)
Gene names: PA4315, mvaT
5'-D(*CP*GP*CP*AP*TP*AP*TP*AP*TP*GP*CP*G)-3' Chains: B, C
Molecule details ›
Chains: B, C
Length: 12 nucleotides
Theoretical weight: 3.66 KDa
Source organism: Pseudomonas aeruginosa PAO1
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 63%
Refinement method: simulated annealing
Expression systems:
  • Escherichia coli
  • Not provided

Quick links

Citations

7 review citations

Chromosome organization in bacteria: mechanistic insights into genome structure and function.
Dame et al. (2020)
6 more

3 mentions without citation

Xenogeneic Silencing and Bacterial Genome Evolution: Mechanisms for DNA Recognition Imply Multifaceted Roles of Xenogeneic Silencers.
Duan et al. (2021)
2 more