› 2mxp

Solution NMR

Solution structure of NDP52 ubiquitin-binding zinc finger

Released:
DOI: 10.2210/pdb2mxp/pdb
PDB entry 2mxp coloured by chain, ensemble of 20 models, front view.
PDB entry 2mxp coloured by chain, ensemble of 20 models, side view.
PDB entry 2mxp coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Molecular basis of ubiquitin recognition by the autophagy receptor CALCOCO2.
Xie X, Li F, Wang Y, Wang Y, Lin Z, Cheng X, Liu J, Chen C, Pan L
Autophagy 11 1775-89 (2015)
PMID: 26506893

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171551 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calcium-binding and coiled-coil domain-containing protein 2 Chain: A
Molecule details ›
Chain: A
Length: 33 amino acids
Theoretical weight: 3.89 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q13137 (Residues: 414-446; Coverage: 7%)
Gene names: CALCOCO2, NDP52

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 83%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

12 review citations

Mechanisms of Selective Autophagy.
Zaffagnini et al. (2016)
11 more

3 mentions without citation

Structure biology of selective autophagy receptors.
Kim et al. (2016)
2 more