› 2myx

Solution NMR

Structure of the CUE domain of yeast Cue1

Released:
DOI: 10.2210/pdb2myx/pdb
PDB entry 2myx coloured by chain, ensemble of 20 models, front view.
PDB entry 2myx coloured by chain, ensemble of 20 models, side view.
PDB entry 2myx coloured by chain, ensemble of 20 models, top view.
Source organism: Saccharomyces cerevisiae S288C
Primary publication:
The CUE Domain of Cue1 Aligns Growing Ubiquitin Chains with Ubc7 for Rapid Elongation.
von Delbrück M, Kniss A, Rogov VV, Pluska L, Bagola K, Löhr F, Güntert P, Sommer T, Dötsch V
Mol Cell 62 918-928 (2016)
PMID: 27264873

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-153650 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Coupling of ubiquitin conjugation to ER degradation protein 1 Chain: A
Molecule details ›
Chain: A
Length: 75 amino acids
Theoretical weight: 8.27 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
  • Canonical: P38428 (Residues: 45-115; Coverage: 35%)
Gene names: CUE1, KIS4, YM8156.06, YMR264W
Sequence domains: CUE domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 92%
Refinement method: molecular dynamics
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Ubiquitin-like Protein Conjugation: Structures, Chemistry, and Mechanism.
Cappadocia et al. (2018)
4 more

1 mention without citation

Ubiquitination in the ERAD Process.
Lopata et al. (2020)