› 2n17

Solution NMR

NMR structure of a Kazal-type serine protease inhibitor from the subterranean termite defense gland of Coptotermes formosanus Shiraki soldiers

Released:
DOI: 10.2210/pdb2n17/pdb
PDB entry 2n17 coloured by chain, ensemble of 10 models, front view.
PDB entry 2n17 coloured by chain, ensemble of 10 models, side view.
PDB entry 2n17 coloured by chain, ensemble of 10 models, top view.
Source organism: Coptotermes formosanus
Primary publication:
A Kazal-Type Serine Protease Inhibitor from the Defense Gland Secretion of the Subterranean Termite Coptotermes formosanus Shiraki.
Negulescu H, Guo Y, Garner TP, Goodwin OY, Henderson G, Laine RA, Macnaughtan MA
PLoS One 10 e0125376 (2015)
PMID: 25978745

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-197686 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Kazal-like domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 75 amino acids
Theoretical weight: 8.58 KDa
Source organism: Coptotermes formosanus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: V9GZ93 (Residues: 1-52; Coverage: 100%)
Sequence domains: Kazal-type serine protease inhibitor domain
Structure domains: Wheat Germ Agglutinin (Isolectin 2); domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 72%
Refinement method: DGSA-distance geometry simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 review citation

A critical review on serine protease: Key immune manipulator and pathology mediator.
Patel S. (2017)
4 other articles

1 mention without citation

A Kazal-Type Serine Protease Inhibitor from the Defense Gland Secretion of the Subterranean Termite Coptotermes formosanus Shiraki.
Negulescu et al. (2015)