› 2n1c

Solution NMR

Structure of PvHCt, an antimicrobial peptide from shrimp litopenaeus vannamei

Released:
DOI: 10.2210/pdb2n1c/pdb
PDB entry 2n1c coloured by chain, ensemble of 20 models, front view.
PDB entry 2n1c coloured by chain, ensemble of 20 models, side view.
PDB entry 2n1c coloured by chain, ensemble of 20 models, top view.
Source organism: Penaeus vannamei
Primary publication:
A hemocyanin-derived antimicrobial peptide from the penaeid shrimp adopts an alpha-helical structure that specifically permeabilizes fungal membranes.
Petit VW, Rolland JL, Blond A, Cazevieille C, Djediat C, Peduzzi J, Goulard C, Bachère E, Dupont J, Destoumieux-Garzón D, Rebuffat S
Biochim Biophys Acta 1860 557-68 (2016)
PMID: 26708991

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-100262 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tyrosinase copper-binding domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 23 amino acids
Theoretical weight: 2.76 KDa
Source organism: Penaeus vannamei
Expression system: Not provided
UniProt:
  • Canonical: A0A059TFW7 (Residues: 654-676; Coverage: 4%)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 50%
Refinement method: simulated annealing
Expression system: Not provided

Quick links

Citations

6 review citations

Shrimp humoral responses against pathogens: antimicrobial peptides and melanization.
Tassanakajon et al. (2018)
5 more

3 mentions without citation

Immunological properties of oxygen-transport proteins: hemoglobin, hemocyanin and hemerythrin.
Coates et al. (2017)
2 more