› 2n5k

Solution NMR

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-176961 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Endoribonuclease ZC3H12A Chain: A
Molecule details ›
Chain: A
Length: 29 amino acids
Theoretical weight: 3.49 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5D1E7 (Residues: 299-327; Coverage: 5%)
Gene names: Mcpip, Mcpip1, Zc3h12a

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this NMR entry.
Chemical shift assignment: 83%
Refinement method: distance geometry, torsion angle dynamics
Expression system: Escherichia coli

Quick links

Citations

13 review citations

RNA-binding proteins in immune regulation: a focus on CCCH zinc finger proteins.
Fu et al. (2017)
12 more

1 mention without citation

Structural basis for the regulation of enzymatic activity of Regnase-1 by domain-domain interactions.
Yokogawa et al. (2016)