› 2n5p

Solution NMR

Universal base control oligonucleotide structure

Released:
DOI: 10.2210/pdb2n5p/pdb
PDB entry 2n5p coloured by chain, front view.
PDB entry 2n5p coloured by chain, side view.
PDB entry 2n5p coloured by chain, top view.
Source organism: synthetic construct
Primary publication:
Using NMR and molecular dynamics to link structure and dynamics effects of the universal base 8-aza, 7-deaza, N8 linked adenosine analog.
Spring-Connell AM, Evich MG, Debelak H, Seela F, Germann MW
Nucleic Acids Res 44 8576-8587 (2016)
PMID: 27566150

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-115652 (preferred)
Entry contents:
2 distinct DNA molecules
Macromolecules (2 distinct):
DNA_(5'-D(*AP*TP*GP*GP*AP*GP*CP*TP*C)-3') Chain: A
Molecule details ›
Chain: A
Length: 9 nucleotides
Theoretical weight: 2.76 KDa
Source organism: synthetic construct
Expression system: Not provided
DNA_(5'-D(*GP*AP*GP*CP*TP*CP*CP*AP*T)-3') Chain: B
Molecule details ›
Chain: B
Length: 9 nucleotides
Theoretical weight: 2.72 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 34%
Refinement method: molecular dynamics, matrix relaxation, distance geometry
Expression system: Not provided

Quick links

Citations

1 review citation

Molecular dynamics simulations and applications in computational toxicology and nanotoxicology.
Selvaraj et al. (2018)
3 other articles

1 mention without citation

Using NMR and molecular dynamics to link structure and dynamics effects of the universal base 8-aza, 7-deaza, N8 linked adenosine analog.
Spring-Connell et al. (2016)