› 2n6u

Solution NMR

Solution study of Astexin2-dC4

Released:
DOI: 10.2210/pdb2n6u/pdb
PDB entry 2n6u coloured by chain, ensemble of 20 models, front view.
PDB entry 2n6u coloured by chain, ensemble of 20 models, side view.
PDB entry 2n6u coloured by chain, ensemble of 20 models, top view.
Source organism: Asticcacaulis excentricus CB 48
Primary publication:
Elucidating the Specificity Determinants of the AtxE2 Lasso Peptide Isopeptidase.
Maksimov MO, Koos JD, Zong C, Lisko B, Link AJ
J Biol Chem 290 30806-12 (2015)
PMID: 26534965

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-123123 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Astexin-2 Chain: A
Molecule details ›
Chain: A
Length: 20 amino acids
Theoretical weight: 2.13 KDa
Source organism: Asticcacaulis excentricus CB 48
Expression system: Escherichia coli
UniProt:
  • Canonical: E8RUP9 (Residues: 26-45; Coverage: 41%)
Gene names: Astex_2448, AtxA2

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 73%
Refinement method: molecular dynamics
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Genome mining for lasso peptides: past, present, and future.
Cheung-Lee et al. (2019)
4 more

2 mentions without citation

Thermal Unthreading of the Lasso Peptides Astexin-2 and Astexin-3.
Allen et al. (2016)
1 more