› 2n7o

Solution NMR

NMR Structure of Peptide PG-990 in DPC micelles

Released:
DOI: 10.2210/pdb2n7o/pdb
PDB entry 2n7o coloured by chain, ensemble of 10 models, front view.
PDB entry 2n7o coloured by chain, ensemble of 10 models, side view.
PDB entry 2n7o coloured by chain, ensemble of 10 models, top view.
Source organism: synthetic construct
Primary publication:
Discovery of Novel Potent and Selective Agonists at the Melanocortin-3 Receptor.
Carotenuto A, Merlino F, Cai M, Brancaccio D, Yousif AM, Novellino E, Hruby VJ, Grieco P
J Med Chem 58 9773-8 (2015)
PMID: 26599352

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-163057 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptide PG-990 Chain: A
Molecule details ›
Chain: A
Length: 10 amino acids
Theoretical weight: 1.13 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
1 modified residue:
Ligand NLE 1 x NLE

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 50%
Refinement method: simulated annealing
Expression system: Not provided

Quick links

Citations

1 review citation

Bench-top to clinical therapies: A review of melanocortin ligands from 1954 to 2016.
Ericson et al. (2017)
11 other articles

1 mention without citation

Discovery of Novel Potent and Selective Agonists at the Melanocortin-3 Receptor.
Carotenuto et al. (2015)