2n9e

Solution NMR

Structure of SUMO-2 bound to phosphorylated RAP80 SIM

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-158461 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
BRCA1-A complex subunit RAP80 Chain: A
Molecule details ›
Chain: A
Length: 15 amino acids
Theoretical weight: 1.58 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q96RL1 (Residues: 37-49; Coverage: 2%)
Gene names: RAP80, RXRIP110, UIMC1
Small ubiquitin-related modifier 2 Chain: B
Molecule details ›
Chain: B
Length: 95 amino acids
Theoretical weight: 10.89 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P61956 (Residues: 1-95; Coverage: 100%)
Gene names: SMT3B, SMT3H2, SUMO2
Sequence domains: Ubiquitin-2 like Rad60 SUMO-like
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Ligands and Environments

No bound ligands
1 modified residue:

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 31%
Refinement method: molecular dynamics, torsion angle dynamics
Expression systems:
  • Not provided
  • Escherichia coli BL21(DE3)