› 2nbr

Solution NMR

The Solution Structure of Human gammaC-crystallin

Released:
DOI: 10.2210/pdb2nbr/pdb
PDB entry 2nbr coloured by chain, ensemble of 20 models, front view.
PDB entry 2nbr coloured by chain, ensemble of 20 models, side view.
PDB entry 2nbr coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Nuclear Magnetic Resonance Structure of a Major Lens Protein, Human γC-Crystallin: Role of the Dipole Moment in Protein Solubility.
Dixit K, Pande A, Pande J, Sarma SP
Biochemistry 55 3136-49 (2016)
PMID: 27187112

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139500 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Gamma-crystallin C Chain: A
Molecule details ›
Chain: A
Length: 173 amino acids
Theoretical weight: 20.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P07315 (Residues: 2-174; Coverage: 99%)
Gene names: CRYG3, CRYGC
Sequence domains: Beta/Gamma crystallin
Structure domains: Crystallins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 74%
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

4 mentions without citation

Chemical Properties Determine Solubility and Stability in βγ-Crystallins of the Eye Lens.
Rocha et al. (2021)
3 more