› 2ncl

Solution NMR

Solution structure of BOLA3 from Homo sapiens

Released:
DOI: 10.2210/pdb2ncl/pdb
PDB entry 2ncl coloured by chain, ensemble of 20 models, front view.
PDB entry 2ncl coloured by chain, ensemble of 20 models, side view.
PDB entry 2ncl coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Mitochondrial Bol1 and Bol3 function as assembly factors for specific iron-sulfur proteins.
Uzarska MA, Nasta V, Weiler BD, Spantgar F, Ciofi-Baffoni S, Saviello MR, Gonnelli L, Mühlenhoff U, Banci L, Lill R
Elife 5 (2016)
PMID: 27532772

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-176114 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
BolA-like protein 3 Chain: A
Molecule details ›
Chain: A
Length: 81 amino acids
Theoretical weight: 9.31 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q53S33 (Residues: 27-107; Coverage: 76%)
Gene name: BOLA3
Sequence domains: BolA-like protein
Structure domains: BolA-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 91%
Refinement method: restrained molecular dynamics
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

15 review citations

Cytosolic iron chaperones: Proteins delivering iron cofactors in the cytosol of mammalian cells.
Philpott et al. (2017)
14 more

8 mentions without citation

Iron-sulfur cluster biogenesis and trafficking in mitochondria.
Braymer et al. (2017)
7 more