› 2ndp

Solution NMR

Structure of DNA-binding HU protein from micoplasma Mycoplasma gallisepticum

Released:
DOI: 10.2210/pdb2ndp/pdb
PDB entry 2ndp coloured by chain, ensemble of 15 models, front view.
PDB entry 2ndp coloured by chain, ensemble of 15 models, side view.
PDB entry 2ndp coloured by chain, ensemble of 15 models, top view.
Source organism: Mycoplasma gallisepticum S6
Primary publication:
Enhanced conformational flexibility of the histone-like (HU) protein from Mycoplasma gallisepticum.
Altukhov DA, Talyzina AA, Agapova YK, Vlaskina AV, Korzhenevskiy DA, Bocharov EV, Rakitina TV, Timofeev VI, Popov VO
J Biomol Struct Dyn 36 45-53 (2018)
PMID: 27884082

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-101272 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA-binding protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 99 amino acids
Theoretical weight: 10.98 KDa
Source organism: Mycoplasma gallisepticum S6
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A0F6CKR5 (Residues: 1-99; Coverage: 100%)
Gene names: GCW_02335, hup_2
Sequence domains: Bacterial DNA-binding protein
Structure domains: IHF-like DNA-binding proteins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 20%
Refinement method: molecular dynamics
Expression system: Escherichia coli

Quick links

Citations

2 citation in other articles

Structure-based inhibitors targeting the alpha-helical domain of the Spiroplasma melliferum histone-like HU protein.
Agapova et al. (2020)
1 more

1 mention without citation

Conserved Apical Proline Regulating the Structure and DNA Binding Properties of Helicobacter pylori Histone-like DNA Binding Protein (Hup).
Agarwal et al. (2022)