› 2neo

Solution NMR

SOLUTION NMR STRUCTURE OF A TWO-BASE DNA BULGE COMPLEXED WITH AN ENEDIYNE CLEAVING ANALOG, 11 STRUCTURES

Released:
DOI: 10.2210/pdb2neo/pdb
PDB entry 2neo coloured by chain, ensemble of 11 models, front view.
PDB entry 2neo coloured by chain, ensemble of 11 models, side view.
PDB entry 2neo coloured by chain, ensemble of 11 models, top view.
Source organism: Synthetic construct
Primary publication:
Solution structure of a two-base DNA bulge complexed with an enediyne cleaving analog.
Stassinopoulos A, Ji J, Gao X, Goldberg IH
Science 272 1943-6 (1996)
PMID: 8658168

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-115662 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-D(*CP*CP*CP*GP*AP*TP*GP*CP*PGE*GP*CP*AP*AP*TP*TP*CP*GP*GP*G)-3') Chain: A
Molecule details ›
Chain: A
Length: 19 nucleotides
Theoretical weight: 5.65 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand NCS 1 x NCS
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DISTANCE GEOMETRY, MOLECULAR DYNAMICS SIMULATIONS
Expression system: Not provided

Quick links

Citations

2 review citations

Natural product DNA major groove binders.
Hamilton et al. (2012)
1 more

1 mention without citation

Three-dimensional modeling of single stranded DNA hairpins for aptamer-based biosensors.
Jeddi et al. (2017)