Protein Data Bank in Europe

Chain: A
Length: 358 amino acids
Theoretical weight: 39.41 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:

• Canonical: Q06265 (Residues: 1-302; Coverage: 69%)

Gene names: EXOSC9, PMSCL1
Sequence domains:

• 3' exoribonuclease family, domain 1
• 3' exoribonuclease family, domain 2

Structure domains: GHMP Kinase, N-terminal domain

Chain: B
Length: 249 amino acids
Theoretical weight: 26.83 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:

• Canonical: Q9NPD3 (Residues: 2-245; Coverage: 100%)

Gene names: EXOSC4, RRP41, SKI6
Sequence domains:

• 3' exoribonuclease family, domain 1
• 3' exoribonuclease family, domain 2

Structure domains: GHMP Kinase, N-terminal domain

Chain: C
Length: 278 amino acids
Theoretical weight: 30.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:

• Canonical: Q96B26 (Residues: 1-276; Coverage: 100%)

Gene names: EXOSC8, OIP2, RRP43
Sequence domains:

• 3' exoribonuclease family, domain 1
• 3' exoribonuclease family, domain 2

Structure domains: GHMP Kinase, N-terminal domain

Chain: D
Length: 237 amino acids
Theoretical weight: 25.48 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:

• Canonical: Q9NQT4 (Residues: 1-235; Coverage: 100%)

Gene names: CML28, EXOSC5, RRP46
Sequence domains:

• 3' exoribonuclease family, domain 1
• 3' exoribonuclease family, domain 2

Structure domains: GHMP Kinase, N-terminal domain

Chain: E
Length: 305 amino acids
Theoretical weight: 33.48 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:

• Canonical: Q15024 (Residues: 1-291; Coverage: 100%)

Gene names: EXOSC7, KIAA0116, RRP42
Sequence domains:

• 3' exoribonuclease family, domain 1
• 3' exoribonuclease family, domain 2

Structure domains: GHMP Kinase, N-terminal domain

Chain: F
Length: 272 amino acids
Theoretical weight: 28.27 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:

• Canonical: Q5RKV6 (Residues: 1-272; Coverage: 100%)

Gene names: EXOSC6, MTR3
Sequence domains: 3' exoribonuclease family, domain 1
Structure domains: GHMP Kinase, N-terminal domain

Chain: G
Length: 289 amino acids
Theoretical weight: 31.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:

• Canonical: Q9NQT5 (Residues: 1-275; Coverage: 100%)

Gene names: CGI-102, EXOSC3, RRP40
Sequence domains:

• Mammalian exosome complex component RRP40, N-terminal
• Exosome complex component RRP40, S1 domain
• KH domain

Structure domains:

• OB fold (Dihydrolipoamide Acetyltransferase, E2P)
• Nucleic acid-binding proteins
• K Homology domain, type 1

Chain: H
Length: 308 amino acids
Theoretical weight: 34.59 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:

• Canonical: Q13868 (Residues: 1-293; Coverage: 100%)

Gene names: EXOSC2, RRP4
Sequence domains:

• KH domain
• Exosome complex exonuclease RRP4 N-terminal region
• RRP4, S1 domain

Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)

Chain: I
Length: 209 amino acids
Theoretical weight: 23.1 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:

• Canonical: Q9Y3B2 (Residues: 1-195; Coverage: 100%)

Gene names: CGI-108, CSL4, EXOSC1
Sequence domains:

• Exosome complex exonuclease RRP4 N-terminal region
• Exosome component EXOSC1/CSL4

Structure domains:

• OB fold (Dihydrolipoamide Acetyltransferase, E2P)
• Nucleic acid-binding proteins