› 2nog

X-ray diffraction
2Å resolution

SANT Domain Structure of Xenopus Remodeling Factor ISWI

Released:
DOI: 10.2210/pdb2nog/pdb
PDB entry 2nog coloured by chain, front view.
PDB entry 2nog coloured by chain, side view.
PDB entry 2nog coloured by chain, top view.
Source organism: Xenopus laevis
Primary publication:
Structure of the SANT domain from the Xenopus chromatin remodeling factor ISWI.
Horton JR, Elgar SJ, Khan SI, Zhang X, Wade PA, Cheng X
Proteins 67 1198-202 (2007)
PMID: 17377988

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179512 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 S homeolog Chains: A, B
Molecule details ›
Chains: A, B
Length: 173 amino acids
Theoretical weight: 20.73 KDa
Source organism: Xenopus laevis
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6DFM0 (Residues: 747-910; Coverage: 16%)
Gene names: ISWI, SNF2H, iswi, smarca5, smarca5.S
Sequence domains: HAND
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand MG 2 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P21
Unit cell:
a: 34.6Å b: 109.5Å c: 46.07Å
α: 90° β: 94.6° γ: 90°
R-values:
R R work R free
0.216 0.212 0.274
Expression system: Escherichia coli

Quick links

Citations

2 review citations

The NuRD architecture.
Allen et al. (2013)
1 more

1 mention without citation

Structure of the SANT domain from the Xenopus chromatin remodeling factor ISWI.
Horton et al. (2007)