› 2ns2

X-ray diffraction
2.2Å resolution

Crystal Structure of Spindlin1

Released:
DOI: 10.2210/pdb2ns2/pdb
PDB entry 2ns2 coloured by chain, front view.
PDB entry 2ns2 coloured by chain, side view.
PDB entry 2ns2 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of human spindlin1. Tandem tudor-like domains for cell cycle regulation.
Zhao Q, Qin L, Jiang F, Wu B, Yue W, Xu F, Rong Z, Yuan H, Xie X, Gao Y, Bai C, Bartlam M, Pei X, Rao Z
J Biol Chem 282 647-56 (2007)
PMID: 17082182

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195335 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Spindlin-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 242 amino acids
Theoretical weight: 27.53 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9Y657 (Residues: 26-262; Coverage: 91%)
Gene names: OCR, SPIN, SPIN1
Sequence domains: Spin/Ssty Family
Structure domains: Spindlin/Ssty

Ligands and Environments

1 bound ligand:
Ligand PO4 2 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P212121
Unit cell:
a: 40.793Å b: 84.876Å c: 136.567Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.236 0.225 0.26
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

4 review citations

Structure and function of histone methylation binding proteins.
Adams-Cioaba et al. (2009)
3 more

10 mentions without citation

(PS)2-v2: template-based protein structure prediction server.
Chen et al. (2009)
9 more