Function and Biology Details
Reactions catalysed:
(3R)-3-hydroxyacyl-[acyl-carrier-protein] + NADP(+) = 3-oxoacyl-[acyl-carrier-protein] + NADPH
(R)-3-hydroxyacyl-CoA + NADP(+) = 3-oxoacyl-CoA + NADPH
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
homo tetramer (preferred)
Assembly name:
3-oxoacyl-[acyl-carrier-protein] reductase MabA (preferred)
PDBe Complex ID:
PDB-CPX-161514 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
3-oxoacyl-[acyl-carrier-protein] reductase MabA
Molecule details ›
Chains: A, B
Length: 267 amino acids
Theoretical weight: 27.93 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Enoyl-(Acyl carrier protein) reductase
Structure domains: NAD(P)-binding Rossmann-like Domain
Length: 267 amino acids
Theoretical weight: 27.93 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P9WGT3 (Residues: 1-247; Coverage: 100%)
Sequence domains: Enoyl-(Acyl carrier protein) reductase
Structure domains: NAD(P)-binding Rossmann-like Domain
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
RIGAKU RU200
Spacegroup:
C2
Expression system: Escherichia coli BL21(DE3)
