› 2nyu

X-ray diffraction
1.76Å resolution

Crystal Structure of Human FtsJ homolog 2 (E.coli) protein in complex with S-adenosylmethionine

Released:
DOI: 10.2210/pdb2nyu/pdb
PDB entry 2nyu coloured by chain, front view.
PDB entry 2nyu coloured by chain, side view.
PDB entry 2nyu coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Dong A, Wu H, Zeng H, Loppnau P, Weigelt J, Sundstrom M, Arrowsmith CH, Edwards AM, Bochkarev A, Plotnikov AN, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193779 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
rRNA methyltransferase 2, mitochondrial Chains: A, B
Molecule details ›
Chains: A, B
Length: 196 amino acids
Theoretical weight: 21.71 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UI43 (Residues: 51-246; Coverage: 80%)
Gene names: FJH1, FTSJ2, MRM2
Sequence domains: FtsJ-like methyltransferase
Structure domains: Vaccinia Virus protein VP39

Ligands and Environments

1 bound ligand:
Ligand SAM 2 x SAM
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P43
Unit cell:
a: 102.022Å b: 102.022Å c: 37.068Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.228 0.226 0.281
Expression system: Escherichia coli

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