› 2o3d

Solution NMR

Structure of human SF2/ASF RNA recognition motif 2 (RRM2)

Released:
DOI: 10.2210/pdb2o3d/pdb
PDB entry 2o3d coloured by chain, ensemble of 20 models, front view.
PDB entry 2o3d coloured by chain, ensemble of 20 models, side view.
PDB entry 2o3d coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Structural and functional analysis of RNA and TAP binding to SF2/ASF.
Tintaru AM, Hautbergue GM, Hounslow AM, Hung ML, Lian LY, Craven CJ, Wilson SA
EMBO Rep 8 756-62 (2007)
PMID: 17668007

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170572 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine/arginine-rich splicing factor 1 Chain: A
Molecule details ›
Chain: A
Length: 113 amino acids
Theoretical weight: 12.93 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q07955 (Residues: 107-215; Coverage: 44%)
Gene names: ASF, OK/SW-cl.3, SF2, SF2P33, SFRS1, SRSF1
Sequence domains: RNA recognition motif
Structure domains: Alpha-Beta Plaits

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

12 review citations

RNA recognition motifs: boring? Not quite.
Cléry et al. (2008)
11 more

3 mentions without citation

Structural and functional analysis of RNA and TAP binding to SF2/ASF.
Tintaru et al. (2007)
2 more