› 2o3j

X-ray diffraction
1.88Å resolution

Structure of Caenorhabditis Elegans UDP-Glucose Dehydrogenase

Released:
DOI: 10.2210/pdb2o3j/pdb
PDB entry 2o3j coloured by chain, front view.
PDB entry 2o3j coloured by chain, side view.
PDB entry 2o3j coloured by chain, top view.
Source organism: Caenorhabditis elegans
Entry authors: Zhang Y, Zhan C, Patskovsky Y, Ramagopal U, Shi W, Toro R, Wengerter BC, Milst S, Vidal M, Burley SK, Almo SC, New York SGX Research Center for Structural Genomics (NYSGXRC)

Function and Biology Details

Reaction catalysed: 
UDP-glucose + 2 NAD(+) + H(2)O = UDP-glucuronate + 2 NADH
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
homo hexamer
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172759 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
UDP-glucose 6-dehydrogenase Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 481 amino acids
Theoretical weight: 52.81 KDa
Source organism: Caenorhabditis elegans
Expression system: Escherichia coli
UniProt:
  • Canonical: Q19905 (Residues: 1-481; Coverage: 100%)
Gene names: F29F11.1, sqv-4
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand GOL 9 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: C2
Unit cell:
a: 159.716Å b: 144.092Å c: 92.072Å
α: 90° β: 123.24° γ: 90°
R-values:
R R work R free
0.21 0.209 0.263
Expression system: Escherichia coli

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