Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- DNA mismatch repair protein MutS, C-terminal
- P-loop containing nucleoside triphosphate hydrolase
- DNA mismatch repair protein MutS, core
- DNA mismatch repair protein MutS, N-terminal
- DNA mismatch repair protein MutS, clamp
- DNA mismatch repair protein MutS, core domain superfamily
- DNA mismatch repair protein MutS, connector domain
- MutS, connector domain superfamily
5 more domains
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
DNA mismatch repair MutSalpha complex and DNA (preferred)
PDBe Complex ID:
PDB-CPX-115717 (preferred)
Entry contents:
2 distinct polypeptide molecules
2 distinct DNA molecules
2 distinct DNA molecules
Macromolecules (4 distinct):
DNA mismatch repair protein Msh2
Molecule details ›
Chain: A
Length: 934 amino acids
Theoretical weight: 104.86 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains:
Structure domains:
Length: 934 amino acids
Theoretical weight: 104.86 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P43246 (Residues: 1-934; Coverage: 100%)
Sequence domains:
Structure domains:
DNA mismatch repair protein Msh6
Molecule details ›
Chain: B
Length: 1022 amino acids
Theoretical weight: 116.06 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains:
Structure domains:
Length: 1022 amino acids
Theoretical weight: 116.06 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical: P52701 (Residues: 341-1360; Coverage: 75%)
Sequence domains:
Structure domains:
