› 2oan

X-ray diffraction
2.61Å resolution

Structure of oxidized beta-actin

Released:
DOI: 10.2210/pdb2oan/pdb
PDB entry 2oan coloured by chain, front view.
PDB entry 2oan coloured by chain, side view.
PDB entry 2oan coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Molecular and structural basis for redox regulation of beta-actin.
Lassing I, Schmitzberger F, Björnstedt M, Holmgren A, Nordlund P, Schutt CE, Lindberg U
J Mol Biol 370 331-48 (2007)
PMID: 17521670

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158078 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Actin, cytoplasmic 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 375 amino acids
Theoretical weight: 41.81 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P60712 (Residues: 1-375; Coverage: 100%)
Gene name: ACTB
Sequence domains: Actin
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand SO4 5 x SO4
Ligand CA 4 x CA
Ligand ATP 4 x ATP
1 modified residue:
Ligand CSD 4 x CSD

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: C2221
Unit cell:
a: 119.174Å b: 222.589Å c: 133.719Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.214 0.21 0.288

Quick links

Citations

28 review citations

Expanding the functional diversity of proteins through cysteine oxidation.
Reddie et al. (2008)
27 more

6 mentions without citation

Edgetic perturbation models of human inherited disorders.
Zhong et al. (2009)
5 more