› 2obd

X-ray diffraction
2.1Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145884 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Cholesteryl ester transfer protein Chain: A
Molecule details ›
Chain: A
Length: 476 amino acids
Theoretical weight: 53.1 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P11597 (Residues: 18-493; Coverage: 100%)
Gene name: CETP
Sequence domains:
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, FUC
Carbohydrate polymer
6 bound ligands:
Ligand CL 1 x CL
Ligand 2OB 2 x 2OB
Ligand PCW 2 x PCW
Ligand EPE 1 x EPE
Ligand 1PE 2 x 1PE
Ligand PG4 1 x PG4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P212121
Unit cell:
a: 66.78Å b: 70.32Å c: 187.62Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.22 0.217 0.265
Expression system: Cricetulus griseus

Quick links

Citations

41 review citations

Recognition of lipopolysaccharide pattern by TLR4 complexes.
Park et al. (2013)
40 more

35 mentions without citation

Electron Tomography: A Three-Dimensional Analytic Tool for Hard and Soft Materials Research.
Ercius et al. (2015)
34 more