› 2ocw

X-ray solution scattering

Solution structure of human secretory component

Released:
DOI: 10.2210/pdb2ocw/pdb
PDB entry 2ocw coloured by chain, ensemble of 10 models, front view.
PDB entry 2ocw coloured by chain, ensemble of 10 models, side view.
PDB entry 2ocw coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of human secretory component and implications for biological function.
Bonner A, Perrier C, Corthésy B, Perkins SJ
J Biol Chem 282 16969-80 (2007)
PMID: 17428798

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134608 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Secretory component Chain: A
Molecule details ›
Chain: A
Length: 585 amino acids
Theoretical weight: 64.36 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P01833 (Residues: 19-603; Coverage: 78%)
Gene name: PIGR
Sequence domains: Immunoglobulin V-set domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Expression system: Cricetulus griseus

Quick links

Citations

5 review citations

The immune geography of IgA induction and function.
Macpherson et al. (2008)
4 more

1 mention without citation

Constrained solution scattering modelling of human antibodies and complement proteins reveals novel biological insights.
Perkins et al. (2009)