› 2ogg

X-ray diffraction
2.5Å resolution

Structure of B. subtilis trehalose repressor (TreR) effector binding domain

Released:
DOI: 10.2210/pdb2ogg/pdb
PDB entry 2ogg coloured by chain, front view.
PDB entry 2ogg coloured by chain, side view.
PDB entry 2ogg coloured by chain, top view.
Source organism: Bacillus subtilis
Primary publication:
The crystal structure of the effector-binding domain of the trehalose repressor TreR from Bacillus subtilis 168 reveals a unique quarternary assembly.
Rezácová P, Krejciríková V, Borek D, Moy SF, Joachimiak A, Otwinowski Z
Proteins 69 679-82 (2007)
PMID: 17705272

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-153952 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH-type transcriptional regulator TreR Chain: A
Molecule details ›
Chain: A
Length: 152 amino acids
Theoretical weight: 18.04 KDa
Source organism: Bacillus subtilis
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P39796 (Residues: 90-238; Coverage: 63%)
Gene names: BSU07820, treR, yfxA
Sequence domains: UTRA domain
Structure domains: Chorismate lyase-like

Ligands and Environments

3 bound ligands:
Ligand NA 1 x NA
Ligand SO4 2 x SO4
Ligand GOL 3 x GOL
1 modified residue:
Ligand MSE 1 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: I4122
Unit cell:
a: 69.719Å b: 69.719Å c: 236.535Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.196 0.19 0.247
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 review citation

Allosteric control of transcription in GntR family of transcription regulators: A structural overview.
Jain D. (2015)
5 other articles

3 mentions without citation

Insight into the induction mechanism of the GntR/HutC bacterial transcription regulator YvoA.
Resch et al. (2010)
2 more