Function and Biology Details
Reactions catalysed:
ATP + a protein = ADP + a phosphoprotein
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151704 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Serine/threonine-protein kinase PLK1
Molecule details ›
Chain: A
Length: 239 amino acids
Theoretical weight: 27.5 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: POLO box duplicated region
Structure domains: POLO box domain
Length: 239 amino acids
Theoretical weight: 27.5 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P53350 (Residues: 365-603; Coverage: 40%)
Sequence domains: POLO box duplicated region
Structure domains: POLO box domain
M-phase inducer phosphatase 3
Molecule details ›
Chain: E
Length: 9 amino acids
Theoretical weight: 917 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 9 amino acids
Theoretical weight: 917 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: P30307 (Residues: 126-134; Coverage: 2%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SLS BEAMLINE X06SA
Spacegroup:
P21
Expression systems:
- Escherichia coli
- Not provided
