› 2okv

X-ray diffraction
2Å resolution

c-Myc DNA Unwinding Element Binding Protein

Released:
DOI: 10.2210/pdb2okv/pdb
PDB entry 2okv coloured by chain, front view.
PDB entry 2okv coloured by chain, side view.
PDB entry 2okv coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure and function of the c-myc DNA-unwinding element-binding protein DUE-B.
Kemp M, Bae B, Yu JP, Ghosh M, Leffak M, Nair SK
J Biol Chem 282 10441-8 (2007)
PMID: 17264083

Function and Biology Details

Reaction catalysed: 
A D-aminoacyl-tRNA + H(2)O = a D-amino acid + tRNA
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-186239 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
D-aminoacyl-tRNA deacylase 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 209 amino acids
Theoretical weight: 23.46 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q8TEA8 (Residues: 1-209; Coverage: 100%)
Gene names: C20orf88, DTD1, DUEB, HARS2
Sequence domains: D-Tyr-tRNA(Tyr) deacylase
Structure domains: D-tyrosyl-tRNA(Tyr) deacylase

Ligands and Environments

1 bound ligand:
Ligand MG 4 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P31
Unit cell:
a: 77.813Å b: 77.813Å c: 106.423Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.206 0.205 0.237
Expression system: Spodoptera frugiperda

Quick links

Citations

2 review citations

Regulation of the initiation step of DNA replication by cyclin-dependent kinases.
Tanaka et al. (2010)
1 more

2 mentions without citation

Ligand-bound structures provide atomic snapshots for the catalytic mechanism of D-amino acid deacylase.
Bhatt et al. (2010)
1 more