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Solution NMR

NMR structure of a kissing complex formed between the TAR RNA element of HIV-1 and a LNA/RNA aptamer

Released:
DOI: 10.2210/pdb2oom/pdb
PDB entry 2oom coloured by chain, ensemble of 12 models, front view.
PDB entry 2oom coloured by chain, ensemble of 12 models, side view.
PDB entry 2oom coloured by chain, ensemble of 12 models, top view.
Source organism: Synthetic construct
Primary publication:
NMR structure of a kissing complex formed between the TAR RNA element of HIV-1 and a LNA-modified aptamer.
Lebars I, Richard T, Di Primo C, Toulmé JJ
Nucleic Acids Res 35 6103-14 (2007)
PMID: 17768146

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-196557 (preferred)
Entry contents:
2 distinct RNA molecules
Macromolecules (2 distinct):
RNA 16-mer Chain: A
Molecule details ›
Chain: A
Length: 16 nucleotides
Theoretical weight: 5.17 KDa
Source organism: Synthetic construct
Expression system: Not provided
TAR RNA element of HIV-1 Chain: B
Molecule details ›
Chain: B
Length: 16 nucleotides
Theoretical weight: 5.14 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
2 modified residues:
Ligand 10C 1 x 10C
Ligand LCA 1 x LCA

Experiments and Validation Details

Entry percentile scores
Expression system: Not provided

Quick links

Citations

9 review citations

RNA Structure: Advances and Assessment of 3D Structure Prediction.
Miao et al. (2017)
8 more

2 mentions without citation

NMR structure of a kissing complex formed between the TAR RNA element of HIV-1 and a LNA-modified aptamer.
Lebars et al. (2007)
1 more