› 2op4

X-ray diffraction
2.85Å resolution

Crystal Structure of Quorum-Quenching Antibody 1G9

Released:
DOI: 10.2210/pdb2op4/pdb
PDB entry 2op4 coloured by chain, front view.
PDB entry 2op4 coloured by chain, side view.
PDB entry 2op4 coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Crystal structures of a quorum-quenching antibody.
Debler EW, Kaufmann GF, Kirchdoerfer RN, Mee JM, Janda KD, Wilson IA
J Mol Biol 368 1392-402 (2007)
PMID: 17400249

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-212300 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Murine Antibody Fab RS2-1G9 Lambda Light Chain Chain: L
Molecule details ›
Chain: L
Length: 212 amino acids
Theoretical weight: 22.91 KDa
Source organism: Mus musculus
Structure domains: Immunoglobulins
Ig-like domain-containing protein Chain: H
Molecule details ›
Chain: H
Length: 222 amino acids
Theoretical weight: 24.08 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: Q5BJZ2 (Residues: 20-118, 119-124, 125-236; Coverage: 49%)
Gene name: LOC367586
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand EDO 1 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: P212121
Unit cell:
a: 56.925Å b: 72.041Å c: 116.143Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.203 0.2 0.263

Quick links

Citations

2 review citations

Quorum quenching: role in nature and applied developments.
Grandclément et al. (2016)
1 more

1 mention without citation

Crystal structures of a quorum-quenching antibody.
Debler et al. (2007)