› 2osa

X-ray diffraction
1.8Å resolution

The Rho-GAP domain of human N-chimaerin

Released:
DOI: 10.2210/pdb2osa/pdb
PDB entry 2osa coloured by chain, front view.
PDB entry 2osa coloured by chain, side view.
PDB entry 2osa coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Walker JR, Hong BS, Shen L, Arrowsmith CH, Sundstrom M, Weigelt J, Edwards AM, Bochkarev A, Park HW, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147515 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
N-chimaerin Chain: A
Molecule details ›
Chain: A
Length: 202 amino acids
Theoretical weight: 23.14 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P15882 (Residues: 260-459; Coverage: 44%)
Gene names: ARHGAP2, CHN, CHN1
Sequence domains: RhoGAP domain
Structure domains: Rho GTPase activation protein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P61
Unit cell:
a: 92.49Å b: 92.49Å c: 47.095Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.19 0.187 0.251
Expression system: Escherichia coli BL21(DE3)

Quick links