› 2oya

X-ray diffraction
1.77Å resolution

Crystal structure analysis of the dimeric form of the SRCR domain of mouse MARCO

Released:
DOI: 10.2210/pdb2oya/pdb
PDB entry 2oya coloured by chain, front view.
PDB entry 2oya coloured by chain, side view.
PDB entry 2oya coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Crystal structure of the cysteine-rich domain of scavenger receptor MARCO reveals the presence of a basic and an acidic cluster that both contribute to ligand recognition.
Ojala JR, Pikkarainen T, Tuuttila A, Sandalova T, Tryggvason K
J Biol Chem 282 16654-66 (2007)
PMID: 17405873

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-178814 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Macrophage receptor MARCO Chains: A, B
Molecule details ›
Chains: A, B
Length: 102 amino acids
Theoretical weight: 11.34 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q60754 (Residues: 421-518; Coverage: 19%)
Gene name: Marco
Sequence domains: Scavenger receptor cysteine-rich domain
Structure domains: SRCR-like domain

Ligands and Environments

1 bound ligand:
Ligand SO4 3 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MAX II BEAMLINE I711
Spacegroup: P1
Unit cell:
a: 31.087Å b: 36.553Å c: 44.605Å
α: 116.3° β: 90.35° γ: 96.41°
R-values:
R R work R free
0.154 0.15 0.191
Expression system: Homo sapiens

Quick links

Citations

10 review citations

Scavenger receptors in homeostasis and immunity.
Canton et al. (2013)
9 more

5 mentions without citation

Macrophage scavenger receptor A mediates adhesion to apolipoproteins A-I and E.
Neyen et al. (2009)
4 more