› 2p4g

X-ray diffraction
2.3Å resolution

CRYSTAL STRUCTURE OF A PYRIMIDINE REDUCTASE-LIKE PROTEIN (DIP1392) FROM CORYNEBACTERIUM DIPHTHERIAE NCTC AT 2.30 A RESOLUTION

Released:
DOI: 10.2210/pdb2p4g/pdb
PDB entry 2p4g coloured by chain, front view.
PDB entry 2p4g coloured by chain, side view.
PDB entry 2p4g coloured by chain, top view.
Source organism: Corynebacterium diphtheriae NCTC 13129
Entry author: Joint Center for Structural Genomics (JCSG)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180044 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Bacterial bifunctional deaminase-reductase C-terminal domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 270 amino acids
Theoretical weight: 29.49 KDa
Source organism: Corynebacterium diphtheriae NCTC 13129
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6NGV8 (Residues: 1-269; Coverage: 100%)
Gene name: DIP1392
Sequence domains: RibD C-terminal domain
Structure domains: Dihydrofolate Reductase, subunit A

Ligands and Environments

2 bound ligands:
Ligand NO3 1 x NO3
Ligand EDO 15 x EDO
1 modified residue:
Ligand MSE 4 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.3, SSRL BEAMLINE BL9-2
Spacegroup: P64
Unit cell:
a: 113.51Å b: 113.51Å c: 55.94Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.175 0.173 0.225
Expression system: Escherichia coli

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