› 2p4w

X-ray diffraction
2.6Å resolution

Crystal structure of heat shock regulator from Pyrococcus furiosus

Released:
DOI: 10.2210/pdb2p4w/pdb
PDB entry 2p4w coloured by chain, front view.
PDB entry 2p4w coloured by chain, side view.
PDB entry 2p4w coloured by chain, top view.
Source organism: Pyrococcus furiosus
Primary publication:
Crystal structure of the archaeal heat shock regulator from Pyrococcus furiosus: a molecular chimera representing eukaryal and bacterial features.
Liu W, Vierke G, Wenke AK, Thomm M, Ladenstein R
J Mol Biol 369 474-88 (2007)
PMID: 17434531

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-186360 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH arsR-type domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 202 amino acids
Theoretical weight: 24.07 KDa
Source organism: Pyrococcus furiosus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8U030 (Residues: 1-202; Coverage: 100%)
Gene name: PF1790
Sequence domains: Bacterial regulatory protein, arsR family
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P21212
Unit cell:
a: 52.389Å b: 82.854Å c: 114.492Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.255 0.252 0.305
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Microbial thermosensors.
Klinkert et al. (2009)
2 more

1 mention without citation

Structural and functional studies of Stf76 from the Sulfolobus islandicus plasmid-virus pSSVx: a novel peculiar member of the winged helix-turn-helix transcription factor family.
Contursi et al. (2014)