› 2paq

X-ray diffraction
2.1Å resolution

Function and Biology Details

Reaction catalysed: 
A 2'-deoxyribonucleoside 5'-monophosphate + H(2)O = a 2'-deoxyribonucleoside + phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo hexamer
Assembly name:
PDBe Complex ID:
PDB-CPX-160095 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
5'-deoxynucleotidase YfbR Chains: A, B
Molecule details ›
Chains: A, B
Length: 201 amino acids
Theoretical weight: 23.26 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
  • Canonical: P76491 (Residues: 1-199; Coverage: 100%)
Gene names: JW2288, b2291, yfbR
Sequence domains: HD domain
Structure domains: Hypothetical protein af1432

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 14 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: R3
Unit cell:
a: 137.023Å b: 137.023Å c: 56.288Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.19 0.187 0.237
Expression system: Escherichia coli

Quick links

Citations

6 review citations

Aicardi-Goutieres syndrome and related phenotypes: linking nucleic acid metabolism with autoimmunity.
Crow et al. (2009)
5 more

3 mentions without citation

Structure and activity of the Cas3 HD nuclease MJ0384, an effector enzyme of the CRISPR interference.
Beloglazova et al. (2011)
2 more