› 2pb9

X-ray diffraction
2.7Å resolution

Crystal structure of C-terminal domain of phosphomethylpyrimidine kinase

Released:
DOI: 10.2210/pdb2pb9/pdb
PDB entry 2pb9 coloured by chain, front view.
PDB entry 2pb9 coloured by chain, side view.
PDB entry 2pb9 coloured by chain, top view.
Source organism: Pyrococcus furiosus
Entry authors: Eswaramoorthy S, Burley SK, Swaminathan S, New York SGX Research Center for Structural Genomics (NYSGXRC)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-186396 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Pyridoxamine kinase/Phosphomethylpyrimidine kinase domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 195 amino acids
Theoretical weight: 22.87 KDa
Source organism: Pyrococcus furiosus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8U193 (Residues: 268-451; Coverage: 41%)
Gene name: PF1333
Sequence domains: Thiamine-phosphate synthase
Structure domains: Class II aldolase/adducin N-terminal domain

Ligands and Environments

1 bound ligand:
Ligand PO4 2 x PO4
1 modified residue:
Ligand MSE 8 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P42212
Unit cell:
a: 78.126Å b: 78.126Å c: 155.388Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.234 0.234 0.291
Expression system: Escherichia coli BL21(DE3)

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