› 2pbz

X-ray diffraction
2.5Å resolution

Crystal structure of an IMP biosynthesis protein PurP from Thermococcus kodakaraensis

Released:
DOI: 10.2210/pdb2pbz/pdb
PDB entry 2pbz coloured by chain, front view.
PDB entry 2pbz coloured by chain, side view.
PDB entry 2pbz coloured by chain, top view.
Source organism: Thermococcus kodakarensis KOD1
Entry authors: Agarwal R, Burley SK, Swaminathan S, New York SGX Research Center for Structural Genomics (NYSGXRC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-177261 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
5-formaminoimidazole-4-carboxamide-1-(Beta)-D-ribofuranosyl 5'-monophosphate synthetase Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 320 amino acids
Theoretical weight: 36.58 KDa
Source organism: Thermococcus kodakarensis KOD1
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5JD28 (Residues: 2-310; Coverage: 100%)
Gene name: TK0431
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand ATP 3 x ATP
1 modified residue:
Ligand MSE 12 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P212121
Unit cell:
a: 63.342Å b: 87.4Å c: 175.907Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.276 0.276 0.3
Expression system: Escherichia coli

Quick links