› 2pco

Solution NMR

Spatial Structure and Membrane Permeabilization for Latarcin-1, a Spider Antimicrobial Peptide

Released:
DOI: 10.2210/pdb2pco/pdb
PDB entry 2pco coloured by chain, ensemble of 20 models, front view.
PDB entry 2pco coloured by chain, ensemble of 20 models, side view.
PDB entry 2pco coloured by chain, ensemble of 20 models, top view.
Source organism: Lachesana tarabaevi
Primary publication:
Three-dimensional structure/hydrophobicity of latarcins specifies their mode of membrane activity.
Dubovskii PV, Volynsky PE, Polyansky AA, Karpunin DV, Chupin VV, Efremov RG, Arseniev AS
Biochemistry 47 3525-33 (2008)
PMID: 18293934

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172819 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
M-zodatoxin-Lt1a Chain: A
Molecule details ›
Chain: A
Length: 26 amino acids
Theoretical weight: 3.21 KDa
Source organism: Lachesana tarabaevi
Expression system: Not provided
UniProt:
  • Canonical: Q1ELT9 (Residues: 63-88; Coverage: 39%)
Sequence domains: Latarcin precursor

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Not provided

Quick links

Citations

7 review citations

Spider-venom peptides: structure, pharmacology, and potential for control of insect pests.
King et al. (2013)
6 more

6 mentions without citation

Recent Progress in the Development of HIV-1 Protease Inhibitors for the Treatment of HIV/AIDS.
Ghosh et al. (2016)
5 more