› 2pcr

X-ray diffraction
2.6Å resolution

Crystal structure of Myo-inositol-1(or 4)-monophosphatase (aq_1983) from Aquifex Aeolicus VF5

Released:
DOI: 10.2210/pdb2pcr/pdb
PDB entry 2pcr coloured by chain, front view.
PDB entry 2pcr coloured by chain, side view.
PDB entry 2pcr coloured by chain, top view.
Source organism: Aquifex aeolicus VF5
Entry authors: Jeyakanthan J, Gayathri D, Velmurugan D, Agari Y, Bessho Y, Ellis MJ, Antonyuk SV, Strange RW, Hasnain SS, Ebihara A, Kuramitsu S, Shinkai A, Shiro Y, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reactions catalysed: 
D-fructose 1,6-bisphosphate + H(2)O = D-fructose 6-phosphate + phosphate
Myo-inositol phosphate + H(2)O = myo-inositol + phosphate
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-130558 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fructose-1,6-bisphosphatase/inositol-1-monophosphatase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 264 amino acids
Theoretical weight: 29.75 KDa
Source organism: Aquifex aeolicus VF5
Expression system: Escherichia coli
UniProt:
  • Canonical: O67791 (Residues: 1-264; Coverage: 100%)
Gene names: aq_1983, imp2, suhB
Sequence domains: Inositol monophosphatase family
Structure domains:

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 32 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX10.1
Spacegroup: P21
Unit cell:
a: 87.001Å b: 68.159Å c: 96.938Å
α: 90° β: 97.86° γ: 90°
R-values:
R R work R free
0.19 0.19 0.247
Expression system: Escherichia coli

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