Function and Biology Details
Reaction catalysed:
Random hydrolysis of (1->4)-linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Hyaluronidase-1 (preferred)
PDBe Complex ID:
PDB-CPX-171396 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Hyaluronidase-1
Molecule details ›
Chain: A
Length: 424 amino acids
Theoretical weight: 47.41 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
Sequence domains: Hyaluronidase
Structure domains: Aldolase class I
Length: 424 amino acids
Theoretical weight: 47.41 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
- Canonical:
Q12794 (Residues: 22-435; Coverage: 100%)
Sequence domains: Hyaluronidase
Structure domains: Aldolase class I
Ligands and Environments
No modified residues
Experiments and Validation Details
wwPDB Validation report is not available for this entry.
X-ray source:
APS BEAMLINE 22-BM
Spacegroup:
P3221
Expression system: Drosophila melanogaster
