› 2pfu

Solution NMR

NMR structure determination of the periplasmic domain of ExbD from E.coli

Released:
DOI: 10.2210/pdb2pfu/pdb
PDB entry 2pfu coloured by chain, ensemble of 19 models, front view.
PDB entry 2pfu coloured by chain, ensemble of 19 models, side view.
PDB entry 2pfu coloured by chain, ensemble of 19 models, top view.
Source organism: Escherichia coli K-12
Primary publication:
The solution structure of the periplasmic domain of the TonB system ExbD protein reveals an unexpected structural homology with siderophore-binding proteins.
Garcia-Herrero A, Peacock RS, Howard SP, Vogel HJ
Mol Microbiol 66 872-89 (2007)
PMID: 17927700

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-142217 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Biopolymer transport protein ExbD Chain: A
Molecule details ›
Chain: A
Length: 99 amino acids
Theoretical weight: 10.91 KDa
Source organism: Escherichia coli K-12
UniProt:
  • Canonical: P0ABV2 (Residues: 43-141; Coverage: 70%)
Gene names: JW2973, b3005, exbD
Sequence domains: Biopolymer transport protein ExbD/TolR
Structure domains: Nucleotidyltransferase; domain 5

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics

Quick links

Citations

3 review citations

Siderophore uptake in bacteria and the battle for iron with the host; a bird's eye view.
Chu et al. (2010)
2 more

14 mentions without citation

One ring to rule them all: Current trends in combating bacterial resistance to the β-lactams.
King et al. (2016)
13 more