› 2pge

X-ray diffraction
1.6Å resolution

Crystal structure of MenC from Desulfotalea psychrophila LSv54

Released:
DOI: 10.2210/pdb2pge/pdb
PDB entry 2pge coloured by chain, front view.
PDB entry 2pge coloured by chain, side view.
PDB entry 2pge coloured by chain, top view.
Source organism: Desulfotalea psychrophila LSv54
Primary publication:
Loss of quaternary structure is associated with rapid sequence divergence in the OSBS family.
Odokonyero D, Sakai A, Patskovsky Y, Malashkevich VN, Fedorov AA, Bonanno JB, Fedorov EV, Toro R, Agarwal R, Wang C, Ozerova ND, Yew WS, Sauder JM, Swaminathan S, Burley SK, Almo SC, Glasner ME
Proc Natl Acad Sci U S A 111 8535-40 (2014)
PMID: 24872444

Function and Biology Details

Reaction catalysed: 
(1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate = 2-succinylbenzoate + H(2)O
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179400 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
o-succinylbenzoate synthase Chain: A
Molecule details ›
Chain: A
Length: 377 amino acids
Theoretical weight: 41.69 KDa
Source organism: Desulfotalea psychrophila LSv54
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6ARP5 (Residues: 2-368; Coverage: 100%)
Gene names: DP0251, menC
Sequence domains: Enolase C-terminal domain-like
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P212121
Unit cell:
a: 59.13Å b: 82.784Å c: 89.578Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.225 0.225 0.238
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Biosynthesis and applications of prenylquinones.
Kawamukai M. (2018)
2 more

2 mentions without citation

Loss of quaternary structure is associated with rapid sequence divergence in the OSBS family.
Odokonyero et al. (2014)
1 more