› 2pik

Solution NMR

CALICHEAMICIN GAMMA1I-DNA COMPLEX, NMR, 6 STRUCTURES

Released:
DOI: 10.2210/pdb2pik/pdb
PDB entry 2pik coloured by chain, ensemble of 6 models, front view.
PDB entry 2pik coloured by chain, ensemble of 6 models, side view.
PDB entry 2pik coloured by chain, ensemble of 6 models, top view.
Source organism: Synthetic construct
Primary publication:
Solution structure of the calicheamicin gamma 1I-DNA complex.
Kumar RA, Ikemoto N, Patel DJ
J Mol Biol 265 187-201 (1997)
PMID: 9020982

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-115767 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecules (2 distinct):
DNA(5'-D(C*AP*CP*TP*CP*CP*TP*GP*GP*TP*TP*TP*TP* TP*GP*TP*GP*AP*GP*GP*AP*CP*CP)-3') Chain: A
Molecule details ›
Chain: A
Length: 23 nucleotides
Theoretical weight: 7.04 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

Carbohydrate polymer : NEW Components: DAG, EMP
Ligand DAG 1 x DAG
Ligand EMP 1 x EMP
4 bound ligands:
Ligand DSR 1 x DSR
Ligand HIB 1 x HIB
Ligand MRP 1 x MRP
Ligand MTC 1 x MTC
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Not provided

Quick links

Citations

13 review citations

A comprehensive review of glycosylated bacterial natural products.
Elshahawi et al. (2015)
12 more

2 mentions without citation

Antibody-drug conjugates: Recent advances in payloads.
Wang et al. (2023)
1 more