› 2plw

X-ray diffraction
1.7Å resolution

Crystal structure of a ribosomal RNA methyltransferase, putative, from Plasmodium falciparum (PF13_0052).

Released:
DOI: 10.2210/pdb2plw/pdb
PDB entry 2plw coloured by chain, front view.
PDB entry 2plw coloured by chain, side view.
PDB entry 2plw coloured by chain, top view.
Source organism: Plasmodium falciparum 3D7
Entry authors: Wernimont AK, Hassanali A, Lin L, Lew J, Zhao Y, Ravichandran M, Wasney G, Vedadi M, Kozieradzki I, Schapira M, Bochkarev A, Edwards AM, Arrowsmith CH, Weigelt J, Sundstrom M, Hui R, Qiu W, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-184756 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
rRNA methyltransferase 2, mitochondrial Chain: A
Molecule details ›
Chain: A
Length: 201 amino acids
Theoretical weight: 23.38 KDa
Source organism: Plasmodium falciparum 3D7
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8IEL9 (Residues: 70-270; Coverage: 70%)
Gene name: PF3D7_1309600
Sequence domains: FtsJ-like methyltransferase
Structure domains: Vaccinia Virus protein VP39

Ligands and Environments

2 bound ligands:
Ligand SO4 1 x SO4
Ligand SAM 1 x SAM
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F1
Spacegroup: P212121
Unit cell:
a: 42.595Å b: 59.798Å c: 71.295Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.205 0.202 0.247
Expression system: Escherichia coli

Quick links