› 2q2g

X-ray diffraction
1.9Å resolution

Crystal structure of dimerization domain of HSP40 from Cryptosporidium parvum, cgd2_1800

Released:
DOI: 10.2210/pdb2q2g/pdb
PDB entry 2q2g coloured by chain, front view.
PDB entry 2q2g coloured by chain, side view.
PDB entry 2q2g coloured by chain, top view.
Source organism: Cryptosporidium parvum Iowa II
Entry authors: Wernimont AK, Lew J, Lin L, Hassanali A, Kozieradzki I, Wasney G, Vedadi M, Walker JR, Zhao Y, Schapira M, Bochkarev A, Weigelt J, Sundstrom M, Arrowsmith CH, Edwards AM, Hui R, Brokx S, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-107142 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
J domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 180 amino acids
Theoretical weight: 20.52 KDa
Source organism: Cryptosporidium parvum Iowa II
Expression system: Escherichia coli
UniProt:
  • Canonical: A3FQ69 (Residues: 148-326; Coverage: 55%)
Gene name: cgd2_1800
Sequence domains: DnaJ C terminal domain
Structure domains: Urease metallochaperone UreE, N-terminal domain

Ligands and Environments

1 bound ligand:
Ligand SO4 2 x SO4
1 modified residue:
Ligand MSE 4 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D, CHESS BEAMLINE A1
Spacegroup: C2
Unit cell:
a: 162.48Å b: 60.59Å c: 48.83Å
α: 90° β: 106.19° γ: 90°
R-values:
R R work R free
0.249 0.249 0.291
Expression system: Escherichia coli

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