2q2r

X-ray diffraction
2.1Å resolution

Trypanosoma cruzi glucokinase in complex with beta-D-glucose and ADP

Released:
Model geometry
Fit model/data

Function and Biology Details

Reaction catalysed:
ATP + D-glucose = ADP + D-glucose 6-phosphate
Biochemical function:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-175499 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glucokinase 1, putative Chains: A, B
Molecule details ›
Chains: A, B
Length: 373 amino acids
Theoretical weight: 41.11 KDa
Source organism: Trypanosoma cruzi
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q4E4E1 (Residues: 1-195, 196-367; Coverage: 97%)
Gene name: Tc00.1047053510187.100
Sequence domains: Glucokinase
Structure domains:

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup: P21212
Unit cell:
a: 107.937Å b: 125.697Å c: 65.112Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.197 0.194 0.258
Expression system: Escherichia coli BL21